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sniff-mcp

Canine genetics and disease knowledge lookups

4039 ms

answered our call

State
Answered
Protocol
MCP 2025-06-18
Tools listed
18
Answered
3 of the last 3 calls

How to reach it

  • MCP, HTTPhttps://mcp.sniff.world/mcp/

What it can do

ToolWhat it says it does
askAsk Sniff a natural-language canine-genetics question and get a GROUNDED, CITED answer (or an honest abstain). Covers inherited diseases (OMIA) and their human homologs (the dog<->human disease bridge), breed disease/carrier risk, variant pathogenicity grades (AVCG; Boeykens et al. 2024, curated…
ask_the_graphTHE INSTRUMENT — ask a free-form CROSS-SPECIES genetics question and get FILTERED, HONEST HINTS (never a confident guess). It compiles your question into a typed query plan over the dog<->human edge-graph, runs it deterministically, and scores each answer PATH by its weakest edge — returning…
ask_variant_contextTHE headline query. Given a CanFam4 position (e.g. '5:56189113'), return the variant's global + popmax frequency, breed-stratified cross-breed frequencies, Pangolin and phyloP annotations, gene context, linked diseases (v1.1), provenance, and deep links — in one call. Pass breed_context to…
breed_similarityGenetic distance between two breeds (top-10-PC Euclidean). Lower = more genetically similar.
breed_summaryBreed profile: n_dogs, breed group, genetic geometry and nearest breeds. Descriptive only — not a health ranking.
breed_variant_frequencyBreed-stratified allele frequency. Give a breed (e.g. 'bernese_mountain_dog') plus either a variant position or a gene symbol. Returns AF (+ rank) for the variant, or per-variant AFs in the gene.
breeds_in_atlasList all 188 breeds with breed-stratified frequencies in the atlas.
disease_bridgeThe fused OMIA disease layer as cited atoms. Give a `disease` (name or 'OMIA:001870-9615') for its genes, inheritance, human homolog (OMIM/Mondo bridge), and variant pathogenicity grade (AVCG, ACMG/AMP 5-tier, curated in OMIA) when graded. Or give a `breed` (e.g. 'doberman_pinscher') for the…
disease_linksA canine inherited disease (name or OMIA id) -> its governed OMIA clinical record: mode of inheritance, causal gene(s), curated description (summary / clinical features / molecular genetics / pathology / prevalence), clinical signs as HP/MP phenotype terms (-> Monarch), the human OMIM analog +…
disease_lookupLook up a canine inherited disease by name or OMIA id -> its governed OMIA clinical record (inheritance, causal gene(s), curated description, clinical signs, human OMIM analog + Mondo id, evidence base). Sourced to OMIA (CC-BY); returns a canonical sniff.world URL. Dog-only. For candidate…
gene_summaryVariants in a gene (by gene symbol), ranked by impact then allele frequency. Paginated (limit, default 25); returns total_variants. Use af_min to filter by global AF.
genes_indexedTop genes by number of variants in the atlas (discovery aid).
metadataAtlas metadata: release, DOI, assembly, variant/breed counts, scope banner, and the RPC catalog.
nearest_breedsGenetically nearest breeds to the given breed (top-10-PC Euclidean in canine genetic space). Answers 'what breeds are most genetically similar to X?' via the PCA-256 breed co-embedding.
search_diseasesSearch the canine disease catalogue by free text -> ranked candidates [{omia_id, disease, url, score}]. Use before disease_lookup when the exact name is unknown. Dog-only.
semantic_searchFaceted hybrid + semantic-ranker search over the whole knowledge base (diseases, breeds, Scout discoveries). Use for fuzzy/thematic intent ('drug sensitivity in herding dogs', 'breeds prone to eye disease', 'genetically diverse breeds'). entity_type filters to 'disease'|'breed'|'discovery'…
variant_lookupSingle-variant lookup by CanFam4 position: ref/alt, global + popmax AF, consequence, gene, Pangolin and phyloP annotations, canonical URL, provenance.
variant_searchFiltered discovery over all 9.67M variants. Predicates (combine freely): phylop_min (phyloP >=), popmax_min (popmax AF >=), gene_in (list of gene symbols), consequence, impact (HIGH/MODERATE/LOW/MODIFIER). Returns total_count + a capped list (max 200). Note: popmax may be in a wild population…

In its maker's words

Canine genomics for agents: breed allele frequencies, AI pathogenicity + OMIA clinical disease layer

Website
sniff.world
Source
github.com/Sniffscore/sniff-mcp
Publisher
sniff.world
Listed from
the official MCP Registry as world.sniff/sniff-mcp
Version
1.1.0, updated 2 Jul 2026
Kinds of work
Health and science, AI models and agent tools

The domain it lives on

sniff.world
registered 28 May 2026 (5 months ago), at Cloudflare, Inc, its name does not resolve now

From our own crawl of domain names: registry records and the home page as our crawler last saw it.

Every call we made

WhenWhat happenedTime
Answered4039 ms
Answered4789 ms
Answered1609 ms

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