bots.st/genebe
GeneBe
Annotate and classify human variants
3290 ms
answered our call
- State
- Answered
- Protocol
- MCP 2025-06-18
- Tools listed
- 6
- Answered
- 3 of the last 3 calls
How to reach it
- MCP, HTTP
https://mcp.genebe.net/v1/mcp
What it can do
| Tool | What it says it does |
|---|---|
annotate_variant | Annotate and classify one human genetic variant using GeneBe. Start here for any question about a variant (what is it, is it pathogenic/benign, how common is it). Returns the ACMG verdict with points and criteria, population frequency (gnomAD), predictor scores (REVEL, AlphaMissense, SpliceAI… |
convert_variant | Convert a variant written in any notation into normalized hg38 genomic coordinates. Use when you only need the chr/pos/ref/alt of a variant (for example to translate HGVS or an rsID), without annotation. Does not classify the variant; use annotate_variant for that. |
explain_acmg_decision_path | Explain step by step why each classification criterion did or did not apply to a variant. Use after annotate_variant when the user asks "why was this classified that way?". Returns an ASCII rendering of the decision tree with the evaluated conditions. By default it explains the germline ACMG… |
get_gene | Look up a human gene: identifiers, location, MANE Select transcript, ClinGen gene-disease validity. Use for questions about a gene rather than a specific variant. Transcripts are listed with MANE Select first and capped; check total_transcripts. |
get_variant_effects | List a variant's predicted molecular consequences on every overlapping transcript. Returns per-transcript HGVS (c. and p.), consequence terms (e.g. missense_variant) and impact, most severe and MANE Select transcripts first. Lightweight: no frequencies or classification. |
liftover_coordinate | Convert a genomic position, interval or variant between genome builds (hg19, hg38, t2t). Check `status`: RESOLVED means one result, AMBIGUOUS means several candidates, anything else means it could not be mapped (see errors). For variants, ref/alt are rebuilt against the target reference and… |
In its maker's words
Annotate and classify human genetic variants with GeneBe (ACMG, gnomAD, ClinVar). Research use only.
- Website
- genebe.net
- Source
- github.com/genebe-net/genebe-mcp
- Publisher
- genebe.net
- Listed from
- the official MCP Registry as
net.genebe/genebe-mcp - Version
- 0.1.0, updated 22 Oct 2026
- Kinds of work
- AI models and agent tools, Documents and files, Data and databases
The domain it lives on
- genebe.net
- registered 19 Sep 2022 (4 years ago), at OVH sas, its name does not resolve now
From our own crawl of domain names: registry records and the home page as our crawler last saw it.
Every call we made
| When | What happened | Time |
|---|---|---|
| Answered | 3290 ms | |
| Answered | 3516 ms | |
| Answered | 1879 ms |
Next door
- WhiteMagic — governed local memory for agent continuityGoverned local agent memory reads and writes
- PolyrankTrader metrics, rankings, and strategy backtests
- DiffCIValidate DiffCI reports and plan affected tests
- FOGA nodeResolve agent identities and safety verdicts, simulate and r
- Mind Upload AI meta harnessRoute coding work through saved memories
Is this your bot? Claim its address to add a verified badge and keep the listing current.